Overview
SLU-PP-332 is a synthetic small-molecule agonist of the estrogen-related receptors (ERRα, with activity at ERRβ and ERRγ), developed at Saint Louis University in the Burris laboratory. ERRs are orphan nuclear receptors that regulate genes involved in mitochondrial biogenesis and oxidative metabolism. Supplied in capsule form for preclinical research.
Research background
The key papers are Billon et al. (2023, Journal of Pharmacology and Experimental Therapeutics) and related work from the Burris group, which characterised SLU-PP-332 as a pan-ERR agonist and reported changes in skeletal-muscle oxidative gene expression and exercise-endurance endpoints in mice. It is used as a tool compound in nuclear-receptor and mitochondrial-metabolism research. All published data are preclinical.
Specifications
| Target | Estrogen-related receptors ERRα/β/γ (agonist) |
| Purity (HPLC) | ≥ 99% — see lot certificate |
| Form | Capsules, 1 mg each |
| Storage | Room temperature, dry, protected from light |
Certificate of analysis
Every lot is tested by an independent US laboratory. The certificate for the lot you receive is linked in the product details above and carries the same lot number as the vial label. New to reading one? How to read a peptide certificate of analysis.
Handling and storage
Store dry at room temperature, protected from light, in the original container.
Frequently asked questions
Is SLU-PP-332 a peptide?
No — it is a small organic molecule. It is listed here because it is used alongside peptides in metabolic research.
What is an ERR agonist?
A compound that activates the estrogen-related receptors, a family of orphan nuclear receptors that regulate mitochondrial and oxidative-metabolism genes. They are not estrogen receptors despite the name.
Storage?
Dry, room temperature, away from light.
Is it tested?
Yes — identity and purity are on the lot certificate linked above.
Human or veterinary use?
No. Research use only.
Research use only. All products are supplied for in-vitro and preclinical laboratory research only. Not for human or veterinary use, not for diagnostic or therapeutic use. Purchaser must be 21+ and accept the Research Use Acknowledgement.
