Overview
Tesamorelin is a synthetic 44-amino-acid analogue of growth-hormone-releasing hormone (GHRH 1-44) with a trans-3-hexenoyl group on the N-terminal tyrosine, which protects the peptide from dipeptidyl-peptidase cleavage. Supplied as a lyophilised powder for neuroendocrine and receptor-pharmacology research.
Research background
Tesamorelin is a well-characterised GHRH-receptor agonist. The published literature includes receptor-binding and signalling studies, pharmacokinetic work on the stabilised N-terminus, and clinical trials conducted by its originator in a specific patient population. This product is the research-grade peptide for laboratory use and is not the approved medicine; results from that programme are cited in the literature for context only.
Specifications
| Structure | (trans-3-hexenoyl)-GHRH(1-44)-NH2 |
| Molecular formula | C221H366N72O67S |
| Molecular weight | ≈ 5,136 g/mol |
| Purity (HPLC) | ≥ 99% — see lot certificate |
| Form | Lyophilised powder, 5 mg |
| Solubility | Water, bacteriostatic water |
| Storage (lyophilised) | −20 °C, desiccated, protected from light |
Certificate of analysis
Every lot is tested by an independent US laboratory. The certificate for the lot you receive is linked in the product details above and carries the same lot number as the vial label. New to reading one? How to read a peptide certificate of analysis.
Handling and storage
Store the lyophilised powder at −20 °C, sealed and protected from light, and bring the vial to room temperature before opening. After reconstitution keep the solution at 2–8 °C in the dark. See how to reconstitute a lyophilised peptide (with calculator) and peptide storage and shelf life.
Frequently asked questions
What makes tesamorelin different from native GHRH?
The N-terminal hexenoyl modification, which resists enzymatic cleavage and extends the peptide’s stability in published assays.
Is this the pharmaceutical product?
No. This is a research-use-only peptide supplied for laboratory work.
Stability?
It contains methionine; protect from oxidation by keeping solutions cold, dark and freshly prepared.
Certificate?
Lot-matched, linked above.
Human or veterinary use?
No. Research use only.
Research use only. All products are supplied for in-vitro and preclinical laboratory research only. Not for human or veterinary use, not for diagnostic or therapeutic use. Purchaser must be 21+ and accept the Research Use Acknowledgement.
