Overview
GLP3-RT is a synthetic 39-amino-acid research peptide engineered as a triple agonist at the GLP-1, GIP and glucagon receptors, with a fatty-diacid side chain for albumin binding. Supplied as a lyophilised powder for receptor-pharmacology and metabolic research.
Research background
Triple GLP-1/GIP/glucagon receptor agonism extends the dual-agonist concept by adding glucagon-receptor activity, which is studied for its effects on energy expenditure in rodent models. The literature on this class includes receptor-selectivity and signalling studies and clinical programmes run by pharmaceutical originators on their proprietary molecules. This product is the research chemical only and is not any approved medicine.
Specifications
| Class | GLP-1 / GIP / glucagon receptor triple agonist peptide |
| Length | 39 amino acids, fatty-diacid acylated |
| Molecular weight | ≈ 4,731 g/mol |
| Purity (HPLC) | ≥ 99% — see lot certificate |
| Form | Lyophilised powder, 10 mg |
| Solubility | Water, bacteriostatic water |
| Storage (lyophilised) | −20 °C, desiccated, protected from light |
Certificate of analysis
Every lot is tested by an independent US laboratory. The certificate for the lot you receive is linked in the product details above and carries the same lot number as the vial label. New to reading one? How to read a peptide certificate of analysis.
Handling and storage
Store the lyophilised powder at −20 °C, sealed and protected from light, and bring the vial to room temperature before opening. After reconstitution keep the solution at 2–8 °C in the dark. See how to reconstitute a lyophilised peptide (with calculator) and peptide storage and shelf life.
Frequently asked questions
How does a triple agonist differ from a dual agonist?
It adds glucagon-receptor activity to GIP and GLP-1 receptor activity. Glucagon-receptor signalling is studied in the literature for its effect on energy expenditure.
Is this an approved medicine?
No. Research-use-only peptide; not a pharmaceutical product.
Stability?
Acylated peptides are relatively robust lyophilised; in solution keep cold and dark and avoid repeated freeze–thaw.
Certificate?
Lot-matched certificate linked above.
Human or veterinary use?
No. Research use only.
Research use only. All products are supplied for in-vitro and preclinical laboratory research only. Not for human or veterinary use, not for diagnostic or therapeutic use. Purchaser must be 21+ and accept the Research Use Acknowledgement.
